Studies on identification of anti-adipogenic (WAT browning) phytochemicals
Therapeutic application of phytochemcials in the obesity and metabolic diseases
Elucidation of molecular mechanisms of anti-adipogenic phytochemicals in adipocytes
Journal Articles
(2021)
Butein-Enriched Fractions of Butea monosperma (Lam.) Taub. Flower Decrease Weight Gains and Increase Energy Expenditure in High-Fat Diet-Induced Obese Mice.
JOURNAL OF MEDICINAL FOOD.
24,
12
(2021)
A Role of Stress Sensor Nrf2 in Stimulating Thermogenesis and Energy Expenditure.
BIOMEDICINES.
9,
9
(2021)
Nrf2 induces Ucp1 expression in adipocytes in response to beta 3-AR stimulation and enhances oxygen consumption in high-fat diet-fed obese mice.
BMB REPORTS.
54,
8
(2020)
Sesamol Increases Ucp1 Expression in White Adipose Tissues and Stimulates Energy Expenditure in High-Fat Diet-Fed Obese Mice.
NUTRIENTS.
12,
5
(2019)
Identification of Phf16 and Pnpla3 as new adipogenic factors regulated by phytochemicals.
JOURNAL OF CELLULAR BIOCHEMISTRY.
120,
3
(2019)
Oxyresveratrol Increases Energy Expenditure through Foxo3a-Mediated Ucp1 Induction in High-Fat-Diet-Induced Obese Mice.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
20(1),
26
(2019)
Sulfuretin Prevents Obesity and Metabolic Diseases in Diet Induced Obese Mice.
BIOMOLECULES & THERAPEUTICS.
27,
1
(2018)
Atf3 induction is a therapeutic target for obesity and metabolic diseases.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.
504,
4
(2018)
PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice.
CELL DEATH & DISEASE.
9,
9
(2017)
Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules.
EXPERIMENTAL AND MOLECULAR MEDICINE.
49,
(2016)
Small Molecule-Induced Complement Factor D (Adipsin) Promotes Lipid Accumulation and Adipocyte Differentiation.
PLOS ONE.
11,
9
(2016)
Prdm4 induction by the small molecule butein promotes white adipose tissue browning.
NATURE CHEMICAL BIOLOGY.
12,
7
(2016)
B cell translocation gene 2 (Btg2) is regulated by Stat3 signaling and inhibits adipocyte differentiation.
MOLECULAR AND CELLULAR BIOCHEMISTRY.
413,
1-2
(2016)
Notch1 deficiency decreases hepatic lipid accumulation by induction of fatty acid oxidation.
SCIENTIFIC REPORTS.
6,
19377
(2016)
Antiadipogenic and proosteogenic effects of luteolin, a major dietary flavone, are mediated by the induction of DnaJ (Hsp40) Homolog, Subfamily B, Member 1.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY.
30,
1
(2015)
Aqueous extracts of hulled barley containing coumaric acid and ferulic acid inhibit adipogenesis in vitro and obesity in vivo.
JOURNAL OF FUNCTIONAL FOODS.
12,
(2015)
Sulfuretin induces osteoblast differentiation through activation of TGF-beta signaling.
MOLECULAR AND CELLULAR BIOCHEMISTRY.
410,
1-2
(2015)
miR-195a Inhibits Adipocyte Differentiation by Targeting the Preadipogenic Determinator Zfp423.
JOURNAL OF CELLULAR BIOCHEMISTRY.
116,
11
(2013)
Dichloromethane extracts of Sophora japonica L. stimulate osteoblast differentiation in mesenchymal stem cells.
NUTRITION RESEARCH.
33,
12
Patent/Intellectual Property
COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME.
14/745.772.
20170124.
UNITED STATES
